Our Science

The Science Behind PRISMM Earth Products

Our team of scientists and doctors are always focused on creating the most effective products to help our patients. With PRISMM Earth, we’re bringing their focus and attention to detail to you.

And they are focused on two key areas:

  1. Developing carefully crafted products. They have decades of experience in carefully developing products with the highest quality, organic ingredients that achieve the best results. 
  2. Effective consumption forms. There are benefits to taking supplements in one form or another (for example, taking a capsule versus a spray).  The form, or product type, has a huge impact on how it can work for you.

We know the benefits of taking a product in one form or the other. Whether you take the product is in a pill form, or it’s a lozenge that allows swift absorption of certain compounds directly into the bloodstream. Or, perhaps a topical application is going to be best for you, where CBD has been proven effective against skin inflammation due to its anti-inflammatory properties. We use that knowledge to create products that will work best for you.

PRISMM Earth Product Ingredients

Our ingredients are carefully sourced from medical-grade products, and our hemp is grown on an organic farm, in soil that has never been touched by industrial pesticides or chemicals.  

Each of our products is formulated with the intention of bringing your body into balance, in the area that might be most bothering you. 

Our team of medical professionals has applied their experience and insights to carefully develop each product with the care and precision that makes them the renowned healthcare professionals they are.

They know what will help reduce inflammation.

They know how to combat environmental factors that might be compromising your immune system.

And they know what combination of active ingredients will help your brain calm down enough to help you fall asleep easily and effortlessly when your head hits the pillow at night.

Organic Hemp Farm

But what goes into each carefully crafted product isn’t where the science ends. 

How your products are administered, or consumed is also a critical component to the effects you may feel after taking them.

Method Of Administration (Or Delivery Systems)

You want to feel better quickly and achieve your therapeutic and wellness goals. To help you achieve this, we developed our products in several different delivery systems to find the best way for you to get the most out of every dose.

PRISMM Earth Dream On Capsules

Making Every Dose Count

The doctors and scientists at PRISMM Earth are dedicated to helping you absorb as many of the active ingredients as possible. 

Each person is different, and all of us respond differently to the various types of delivery systems. For example, your response to taking a capsule will be different than if you use a spray or a topical that you rub on your skin. And your response will be different from the person sitting closest to you.

That’s why it’s important to understand what is best for you!

To help, we cornered our Compounding Pharmacists to share their insights about how each type of delivery system works so you can decide what will be best for you. 

The Science of Product Form and Delivery Systems

We’re going to get technical for a few minutes, so if you’re interested in the science behind our product delivery systems, then this information is for you.

It’s important to know that the effectiveness of each product doesn’t only depend on the amount of CBD in a particular delivery system.

Effectiveness is directly related to a product’s Bioavailability (How much active ingredients gets into the body).

  • Bioavailability of a product is dependent upon the following parameters (“Pharmacokinetics”): 
    • Absorption – Amount of the active ingredients that pass through the skin, gastrointestinal tract, or mucus membranes into the body
    • Distribution – Where the active ingredients go in the body
    • Metabolism – How the ingredients are broken down
    • Elimination – How the ingredients are removed through the body, most commonly through the liver and kidneys. 

Bioavailability is mostly dependent on the delivery system, which can affect the time a product takes to act and how long it lasts. We have found that the best results are achieved through: 

  • Oral
  • Transdermal (Topical)

Here is what we need to remember: 

Inverse Relationship of Bioavailability

Our Unique Dosage Forms

PRISMM Earth Transdermal Creams Use Liposomal Delivery

Liposomes are molecules consisting of an outer Lipid (Fat) Bilayer (houses oil-soluble active ingredients) and an inner area that houses solid or water-soluble drugs).

PRISMM Earth’s topical/transdermal creams use a Liposomal base to carry active drugs through all layers of the skin for maximum concentration at the site of application. 

This means that the topical/transdermal products produced by PRISMM Earth have the greatest bioavailability (amount of CBD reaching the target areas) in the world.

  • Liposomal base enhances ingredient penetration through the skin
  • Allows incorporation of multiple ingredients into a base cream
  • Maximizes therapeutic outcomes
Liposomal Delivery

The Science Behind PRISMM Earth Capsules

Our capsule products are carefully formulated for consistency and to create a uniform response.

This means that both the standard release amount and time (onset of action) are always consistent.

This is another PRISMM Earth advantage, all of our products are developed by compounding pharmacists and scientists with decades of experience in ensuring product consistency and reliability.

And who doesn’t want the confidence and peace of mind that comes with knowing that every time you take a capsule, it will be the same as the last? We definitely do, and you do too.

Why are capsules a great option? 

  • Consistency of active ingredients in every capsule and in every bottle
  • Standardization of future products
  • Easy to take
  • Will not leak as opposed to gel capsules
  • Do not contain artificial fillers and binders

This product form can help decrease the number of doses needed during any 24-hour period. This both helps ensure you’ll take them when you need them,  and it saves you money.

Why PRISMM Earth Uses Troches (Lozenges)

The PRISMM Earth Troches are placed between the cheek and gum for optimal absorption. A significant amount of the active ingredients is absorbed directly into the bloodstream through the mucosal lining of the mouth.

Under normal circumstances, only a small amount of a drug is swallowed and absorbed through the Gastro-intestinal Tract.

Benefits of Troches

The benefits of this delivery system include a more rapid onset of action than through the oral route, which bypasses the GI Tract thus eliminating the effects of First Pass Metabolism.

First Pass Metabolism occurs only when a drug is taken orally. The drug goes from the GI Tract directly to the Liver where it is broken down by Liver Enzymes thus reducing the amount of “active” drug up taken by the body.

Why are troches a great option for some products?

  • Similar to lozenges, but is placed between the cheek and gums
  • Improves absorption without potency loss from swallowing
  • More rapid onset of ingredients than capsules or lozenges
  • Uniform absorption of active ingredients

Oral (Sublingual) Spray – Coming Soon!

Coming soon, the PRISMM Earth oral spray products will also have the features of:

  • Sublingual absorption
  • Rapid onset of action
  • Bypassing “First Pass Metabolism” by the Liver
  • A higher amount of active ingredients reach the site(s) of action
  • Provides a standard dosing concentration (mg per spray)

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, nursing, taking any medications or have any medical conditions, consult your doctor before use. Legal age of use/consumption is 21 years of age. Our products do not contain more than the hemp standard of 0.3% THC.